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3D Reconstruction
A wide range of software techniques and advanced computer systems are developed that enable creation of three-dimensional images. Spiral CT allows the acquisition of CT data that is perfectly suited to 3D reconstruction. Advanced CT scanners image entire anatomic regions like the lungs in one breath hold and acquire a volume of data with the patient anatomy all in one position. This volume data is reconstructed to provide 3 dimensional pictures of for example complex blood vessels like the renal arteries or aorta. 3D reconstructions allow surgeons to visualize complex fractures in three dimensions and can help them plan reconstructive surgery.
Beta Decay
There are two kinds of beta decay: beta minus and beta plus decay. The differentiation depends on the charge of the emitted particle.
At the beta plus decay in the nucleus a proton changes to a neutron and emits a positron and a neutrino. The atom is after the decay a different element, but with the same number of particles in the nucleus.
At the beta minus decay in the nucleus a neutron changes to a proton and emits an electron and an antineutrino. As with the beta plus decay the atom changes to a different element but with the same number of particles in the nucleus.
Sometimes the electron capture is mentioned as a third kind of beta decay.
Beta decay is used for example in positron-electron tomography or in iodine-131 therapy.

See also Electron Capture.
Binding Energy
Binding energy is equal to the amount of energy which is used to free electrons or disintegrate nuclides from their atomic bond.
The electron binding energy of a hydrogen atom is with 13.6 eV very low. The nuclear binding energy of an alpha-particle, energy equivalent of the sum of the individual masses of nuclides minus the mass of the whole nucleus, is 28.3 MeV.

See also Alpha Decay, Beta Decay and Gamma Quantum.
Contrast Agents
(CA) Contrast agents are used to change the imaging characteristics, resulting in additional information about anatomy, morphology or physiology of the human body. Radiocontrast agents (also called photon-based imaging agents) are used to improve the visibility of internal body structures in x-ray and CT procedures. Contrast agents are also used to increase the contrast between different tissues in MRI (magnetic resonance imaging) and ultrasound imaging. The ideal imaging agent provides enhanced contrast with little biological interaction.
First investigations with radiopaque materials are done shortly after the discovery of x-rays. These positive contrast agents attenuate x-rays more than body soft tissues due to their high atomic weight. Iodine and barium have been identified as suitable materials with high radiodensity and are used until today in x-ray and CT contrast agents. Iodine-based contrast agents are water-soluble and the solutions are used nearly anywhere in the body. Iodinated contrast materials are most administered intravenous, but can also be introduced intraarterial, intrathecal, oral, rectal, intravesical, or installed in body cavities. Barium sulfate is only used for opacification of the gastrointestinal tract. Negative contrast agents attenuate x-rays less than body soft tissues, for example gas.

Iodinated contrast media are differentiated in;

Intravascular iodinated contrast agents are required for a large number of x-ray and CT studies to enhance vessels and organs dependent on the blood supply. Injectable contrast agents are diluted in the bloodstream and rapidly distributed throughout the extracellular fluid. The main route of excretion is through the kidneys, related to the poor binding of the agent to serum albumin. The liver (gall bladder) and small intestine provide alternate routes of elimination particularly in patients with severe renal impairment. The use of special biliary contrast agents is suitable for gallbladder CT and cholecystograms because they are concentrated by the liver to be detectable in the hepatic bile.
The introduction of fast multi-detector row CT technology, has led to the development of optimized contrast injection techniques. The amount of contrast enhancement depends on the contrast agent characteristics, such as iodine concentration, osmolality, viscosity, and the injection protocol, such as iodine flux and iodine dose. Adverse reactions are rare and have decreased with the introduction of nonionic contrast agents.
See also Contrast Enhanced Computed Tomography, Abdomen CT, Contrast Media Injector, Single-Head CT Power Injector, Multi-Head Contrast Media Injector, Syringeless CT Power Injector, CT Power Injector.
Filtration
X-rays contain a range of energies (polychromatic photons), the higher energies pass through the patient, the lower energies are absorbed or scattered by the body. Ideally, the x-ray beam should be monochromatic or composed of photons having the same energy. Strong filtration of the beam results in more uniformity. The more uniform the beam, the more accurate the attenuation values or CT numbers are for the scanned anatomical region.
There are two types of filtration utilized in CT:
Inherent tube filtration and filters made of aluminum or Teflon are utilized to shape the beam intensity by filtering out the undesirable x-rays with low energy. Filtration of the x-ray beam is usually done by the manufacturer prior to installation. The half value layer provides information about the energy characteristics of the x-ray beam. Too much filtration produces a loss of contrast in the x-ray image.
A mathematical filter such as a bone or soft tissue algorithm is included into the CT reconstruction process to enhance resolution of a particular anatomical region of interest.
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