Radiology - Technology Information PortalTuesday, 30 September 2014
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 'Digital Subtraction Angiography' 
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Digital Subtraction Angiography
 
(DSA) Digital subtraction angiography is a radiographic imaging technique to visualize the blood vessels in the human body. DSA images are produced by the (computer) subtraction of pre-contrast images (the mask) from images after introduction of a contrast medium. Subtracting background structures and enhancing the contrast provides the visualization of blood vessels in a bony or dense soft tissue environment. The images are produced in real time, as the contrast agent is injected into the blood vessels.
 
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Angiography
 
Angiography means the imaging of veins and arteries. The examination is called angiogram.
See also CT Angiography, Coronary Angiogram, Digital Subtraction Angiography, Venography and Magnetic Resonance Angiography MRA.

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Decimation
 
Decimation is the reduction of data at the digitized signal. Fewer samples are used to represent the detected signal. The opposite process is called interpolation, more samples are added.
See also Digital Radiography, and Digital Subtraction Angiography.
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OptirayŽ
 
OptirayŽ is a radiographic contrast agent. OptirayŽ is available in concentrations from 160 to 350 mg/mL organically bound iodine. OptirayŽ solutions have osmolalities 1.2 to 2.8 times that of plasma (285 mOsm/kg water).
OptirayŽ 160 is recommended for intraarterial digital subtraction angiography (IA-DSA).

Drug Information and Specification
NAME OF COMPOUND Ioversol
DEVELOPER Mallinckrodt, Inc.
INDICATION Brain and body computed tomography, urography, angiography
APPLICATION Intravascular
PHARMACOKINETIC Renal excretion
CHEMICAL BOND Nonionic
OSMOLALITY 355, 502, 651, 702, 792 mosm/kgH2O
IODINE CONCENTRATION 160, 240, 300, 320, 350 mg/mL
DOSAGE Depending on the used concentration and imaging procedure
PREPARATION Ready-to-use product
STORAGE Store at 25°C (77°F)
PRESENTATION Depending on the concentration: 20, 30 mL vials, 50, 75, 100, 150, 200 mL bottles,
30, 50 mL prefilled hand held plastic syringes, and various power injector syringes (OptiVantage)
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!


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Optiray Package Insert(.pdf)Open this link in a new window
by imaging.covidien.com    
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Post-Processing
 
Digital images can be manipulated for evaluation in various ways. Post-processing includes: Subtraction, addition, rotation, inversion, multiplanar reconstruction (MPR), maximum intensity projection (MIP), etc.
Subtraction is particularly useful in contrast enhanced examinations. The pre contrast images are subtracted from the images after an injection of contrast agents (sometimes also called dye) for better tumor detection. See also Contrast Enhanced Computed Tomography, Digital Subtraction Angiography and Active Zone.
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