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Searchterm 'Hypaque 76' found in 1 term [
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Hypaque 76
Hypaque 76 is a radiopaque contrast agent supplied as a 76 percent sterile aqueous solution providing 66 percent (w/v) diatrizoate meglumine and 10 percent (w/v) diatrizoate sodium.

Drug Information and Specification
NAME OF COMPOUND
Diatrizoate meglumine, diatrizoate sodium
MANUFACTURER
INDICATION
Urography, angiography, CT head
APPLICATION
Intravascular
PHARMACOKINETIC
Renal excretion
CHEMICAL BOND
2016 mosm/kgH2O
IODINE CONCENTRATION
370 mg/mL
50 mL to 125 mL
PREPARATION
Ready-to-use product
STORAGE
Protect from light. Store at 15°Celsius to 30°C (59° Fahrenheit to 86°F).
PRESENTATION
50 mL vials, 200 mL bottles
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
GE Healthcare has discontinued Hypaque 76 for unknown reasons.
GE Healthcare
www.gehealthcare.com

GE Healthcare is the result of the merger between GE Medical and Amersham Health in Nov. 2004, after GE acquired Amersham Health for 9.5 billion in Oct. 2003. Jeffrey R. Immelt, Chairman of the Board and Chief Executive of General Electric, said, 'Amersham's diagnostic pharmaceutical and life sciences business will add new, high growth platforms to GE Medical's diagnostic imaging, services and health care information technology businesses'. GE Healthcare, a UK company, is a unit of General Electric (NYSE: GE). GE Healthcare is a global leader in medical imaging, diagnostic imaging agents, interventional procedures, health care services, and information technology. For more than 100 years, health care providers have relied on GE Medical Systems, now GE Healthcare, for high quality medical technology and productivity solutions. GE Healthcare, headquartered now at the formerly seat of Amersham Healthcare in Great Britain, operates facilities around the world. Global Operations include organizations on the Americas, Europe, and Asia, including India, Japan, Korea China, Thailand and Vietnam.

CT and X-Ray Related Product Lines: CT Systems
LightSpeed VCT®
LightSpeed Pro®
LightSpeed RT®
LightSpeed Xtra®
BrightSpeed®
HiSpeed®
CT and X-Ray Related Product Lines: Contrast Agents
TRADE NAME
APPROVED
FOR SALE /
DEVELOPMENT
DEVELOPMENT
Contact Information
Ionic Monomer
The first-generation contrast agents were all ionic monomers, consisting of a tri-iodinated benzene ring with 2 organic side chains and a carboxyl group. Diatrizoate or iothalamate are common iodinated anions, conjugated with a cation, sodium or meglumine. The ionization at the carboxyl-cation bond makes the agent water soluble.
Ionic monomers have the highest osmolality (high-osmolar contrast media (HOCM) possess an osmolality seven to eight times higher than plasma) of the different groups of contrast agents (CM ratio=1.5) and the lowest viscosity. The osmolality in solutions of ionic monomers ranges from 600 to 2100 mOsm/kg (human plasma = 290 mOsm/kg). These high osmolality is related to some of the adverse reactions. HOCM's have been widely replaced by newer contrast agents with improved tolerability and safety profiles.
Examples of HOCM's are Renografin®-60, Hypaque 76, Hypaque Meglumine, Hypaque Sodium and Conray®.

See also Ionic Contrast Agents.
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