Imaging refers to the visual representation of an object. Today, diagnostic imaging uses radiology and other techniques, mostly noninvasive, to create pictures of the human body. Diagnostic radiography studies the anatomy and physiology to diagnose an array of medical conditions. The history of medical diagnostic imaging is in many ways the history of radiology. Many imaging techniques also have scientific and industrial applications. Diagnostic imaging in its widest sense is part of biological science and may include medical photography, microscopy and techniques which are not primarily designed to produce images (e.g., electroencephalography and magnetoencephalography).
Brief overview about important developments:
Imaging used for medical purposes, began after the discovery of x-rays by Konrad Roentgen 1896. The first fifty years of radiological imaging, pictures have been created by focusing x-rays on the examined body part and direct depiction onto a single piece of film inside a special cassette.
In the 1950s, first nuclear medicine studies showed the up-take of very low-level radioactive chemicals in organs, using special gamma cameras. This diagnostic imaging technology allows information of biologic processes in vivo. Today, single photon emission computed tomography (SPECT) and positron emission tomography (PET) play an important role in both clinical research and diagnosis of biochemical and physiologic processes.
In the 1960s, the principals of sonar were applied to diagnostic imaging. Ultrasound has been imported into practically every area of medicine as an important diagnostic tool, and there are great opportunities for its further development. Looking into the future, the grand challenges include targeted contrast imaging, real-time 3D or 4D ultrasound, and molecular imaging. The earliest use of ultrasound contrast agents (USCA) was in 1968.
The introduction of computed tomography (CT/CAT) in the 1970s revolutionized medical imaging with cross sectional images of the human body and high contrast between different types of soft tissues. These developments were made possible by analog to digital converters and computers. First, spiral CT (also called helical), then multislice CT (or multi-detector row CT) technology expanded the clinical applications dramatically.
The first magnetic resonance imaging (MRI) devices were tested on clinical patients in 1980. With technological improvements including higher field strength, more open MRI magnets, faster gradient systems, and novel data-acquisition techniques, MRI is a real-time interactive imaging modality that provides both detailed structural and functional information of the body.

Today, imaging in medicine has been developed to a stage that was inconceivable a century ago, with growing modalities:
x-ray projection imaging, including conventional radiography and digital radiography;
All these types of scans are an integral part of modern healthcare. Usually, a radiologist interprets the images. Most clinical studies are acquired by a radiographer or radiologic technologist. In filmless, digital radiology departments all images are acquired and stored on computers. Because of the rapid development of digital imaging modalities, the increasing need for an efficient management leads to the widening of radiology information systems (RIS) and archival of images in digital form in a picture archiving and communication system (PACS). In telemedicine, medical images of MRI scans, x-ray examinations, CT scans and ultrasound pictures are transmitted in real time.

See also Interventional Radiology, Image Quality and CT Scanner.

Fluoroscopy is used to study moving body structures in real time. A fluoroscope is used to produce a continuous (advanced fluoroscopy machines provide pulsed techniques to lower the amount of radiation) x-ray beam, passing through the body part being examined and transmitted to a monitor so that dynamic images of deep tissue structures can be visualized. Fluoroscopy is primarily used for gastrointestinal exams, genitourinary studies, cardiovascular imaging and for invasive procedures performed by interventional radiologists and angiographers under fluoroscopic guidance. Fluoroscopy can also produce a static record of an image formed on the output phosphor of an image intensifier. The image intensifier is an x-ray image receptor that increases the brightness of a fluoroscopic image by electronic amplification and image minification. Modern fluoroscopy systems combine less radiation with better image quality due to digital image processing and flat-panel technology.
Roentgen's discovery of x-rays related directly to fluoroscopy, because fluorescence on the material in the room draws his attention to the x-ray's properties. In 1896, Thomas A. Edison created the first fluoroscope, consisting of a zinc-cadmium sulfide screen that was placed above the patient's body in the x-ray beam and provides a faint fluorescent image. In first-generation units, the exam room required complete darkness. The users wear red goggles for up to 30 minutes prior to the examination, to adapt the eyes to darkness. After this, the radiologist stared directly at a yellow-green fluorescent image through a sheet of lead to prevent the x-ray beam from striking the eyes.

(mrem) One thousandth of a rem.

See Roentgen Equivalent In Man.

X-rays are a part of the electromagnetic spectrum. X-rays and gamma rays are differentiated on the origin of the radiation, not on the wavelength, frequency, or the energy. X-rays are emitted by electrons outside the nucleus, while gamma rays are emitted by the nucleus. X-rays have wavelengths in the range of about 1 nanometer (nm) to 10 picometer (pm), frequencies in the range of 10^-16 to 10^-20 Hertz (Hz) and photon energies between 0.12 and 120 kilo electron Volt (keV). The energy of rays increase with decreased wavelengths. X-rays with energies between 10 keV and a few hundred keV are considered hard X-rays. The cutoff between soft or hard X-rays is around a wavelength of 100 pm.
Because of their short wavelength, X-rays interact little with matter and pass through a wide range of materials. These interactions occur as absorption or scattering;; primary are the photoelectric effect, Compton scattering and, for ultrahigh photon energies of above 1.022 mega electron Volt (MeV), pair production.
X-rays are produced when high energy electrons struck a metal target. The kinetic energy of the electrons is transformed into electromagnetic energy when the electrons are abruptly decelerated (also called bremsstrahlung radiation, or braking radiation) similar to the deceleration of the circulating electron beam in a synchrotron particle accelerator. Another type of rays is produced by the inner, more tightly bound electrons in atoms;; frequently occurring in decay of radionuclides (characteristic radiation, gamma ray, beta ray). The energy of an X-ray is equivalent to the difference in energy of the initial and final atomic state minus the binding energy of the electron.
Wilhelm Conrad Roentgen discovered this type of rays (also called Roentgen-rays) in 1895 and realized that X-rays penetrate soft tissue but are absorbed by bones, which provides the possibility to image anatomic structures; the first type of diagnostic imaging was established. Radiographic images are based on this difference in attenuation for tissue and organs of different density. Today ionizing radiation is widely used in medicine in the field of radiology.

See also Exposure Factors, X-Ray Tube, and X-Ray Spectrum.

The x-ray (or roentgen-ray) spectrum consists of electromagnetic radiation with wavelengths shorter than ultraviolet (UV) and longer than gamma rays. The usual photon energies of x-rays range from 100 electron volt (eV) to 100 keV (wavelengths of around 10 to 0.01 nanometers; or around 100 to 0.1 Angstroms); corresponding to frequencies in the range of 30 PHz to 30 EHz (see Hertz).
The energy distribution (wavelength, frequency) of x-ray photons emerges from the source, the x-ray tube. In a conventional tube, x-rays are generated in two different ways that, together, form a typical spectrum consisting of the bremsstrahlung, which is superimposed by the lines of the characteristic spectrum (in a graph, the curve is shaped like a hump topped by several spikes).

See also Angstrom, Direct Radiation, Secondary Radiation, and Radiation Meter.