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Visipaque
Visipaque is an iso-osmolar contrast agent. The osmolality equal to that of blood and the sodium and calcium concentration in a ratio equivalent to blood provides high patient safety and comfort.

Drug Information and Specification
NAME OF COMPOUND
Iodixanol
DEVELOPER
INDICATION
Brain and body computed tomography, urography, angiography
APPLICATION
Intravascular
PHARMACOKINETIC
Renal excretion
CHEMICAL BOND
290 mosm/kgH2O
IODINE CONCENTRATION
270 and 320 mg/mL
Depending on the used concentration and imaging procedure
PREPARATION
Ready-to-use product
STORAGE
Store at 20°-25°C (68°-77°F); excursions permitted to 15°-30°C (59°-86°F), protect from light.
PRESENTATION
50 mL vials; 50, 100, 150, 200 mL glass or polymer bottles; 100, 125 mL prefilled cartridges
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
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GE Healthcare
www.gehealthcare.com

GE Healthcare is the result of the merger between GE Medical and Amersham Health in Nov. 2004, after GE acquired Amersham Health for 9.5 billion in Oct. 2003. Jeffrey R. Immelt, Chairman of the Board and Chief Executive of General Electric, said, 'Amersham's diagnostic pharmaceutical and life sciences business will add new, high growth platforms to GE Medical's diagnostic imaging, services and health care information technology businesses'. GE Healthcare, a UK company, is a unit of General Electric (NYSE: GE). GE Healthcare is a global leader in medical imaging, diagnostic imaging agents, interventional procedures, health care services, and information technology. For more than 100 years, health care providers have relied on GE Medical Systems, now GE Healthcare, for high quality medical technology and productivity solutions. GE Healthcare, headquartered now at the formerly seat of Amersham Healthcare in Great Britain, operates facilities around the world. Global Operations include organizations on the Americas, Europe, and Asia, including India, Japan, Korea China, Thailand and Vietnam.

CT and X-Ray Related Product Lines: CT Systems
LightSpeed VCT®
LightSpeed Pro®
LightSpeed RT®
LightSpeed Xtra®
BrightSpeed®
HiSpeed®
CT and X-Ray Related Product Lines: Contrast Agents
TRADE NAME
APPROVED
FOR SALE /
DEVELOPMENT
DEVELOPMENT
Contact Information
Nonionic Dimer
A nonionic dimer consists of 2 joined nonionic monomers. Nonionic dimers are used as x-ray and CT contrast media.
Nonionic dimers have the lowest osmolarity. These contrast materials contain 6 iodine atoms for every 1 particle in solution (CM ratio=6). Modern CT techniques require fast bolus injections and thus low-viscosity, high-concentration, well-tolerated contrast agents. Nonionic dimers have the highest viscosity, which limits the clinical usefulness. Examples of nonionic dimers are iotrolan (Isovist®) and iodixanol (Visipaque).

See also Contrast Agents.
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